Diagnostic Tests for Agents of Community- Acquired Pneumonia Essay

Worldwide, lower respiratory tract infections are the major cause of conclusion due to an infectious disease. Community-acquired pneumonia ( top) is possibly the most important infectious disease that is encountered in clinical practice. Most forms of community-acquired pneumonia (CAP) are treatable. There is consensus that the selection of antimicrobial agents is notably simplified if the pathogen is defined. This article will focus on how aetiologic tests skunk be used to guide antibiotic therapy in adult patients with CAP.The role of aetiological testing for antimicrobial therapy in CAPA major role of aetiological testing in CAP is to enable the use of pathogen-directed therapy, and thus sicken the use of broad-spectrum antibiotics and improve the outcome in patients. It has been suggested that the antibiotic therapy should be started within 4 h of hospital admission 4, 8, hence quick tests with a shorter abstract time can be used to influence the choice of first-line anti biotic therapy.Rapid tests include, sputum gram strain, urinary antigen tests, and real-time PCR for respiratory pathogens. Less rapid tests, such as cultures, conventional PCR for respiratory pathogens, and serology, may provide useful information that may choke ongoing antibiotic therapy, support narrowing of broad-spectrum therapy, and support therapy changes in case of treatment failure 3. Culture of blood and respiratory specimens may be important for the identification of unexpected or uncommon CAP aetiologies that the empirical treatment does not cover for, e.g., Pseudomonas spp., methicillin-resistant S. aureus, and other highly resistant pathogens. Culture remains a cornerstone of the diagnostic techniques, as it can provide information abou... ...ing to the BTS and Swedish guidelines 7,8.Suggested strategy for diagnostic testingA strategy for diagnostic testing in hospitalized CAP patients is presented in Table 3. It is establish on disease severity and presence/absence of prior antibiotic therapy.ConclusionIn order to cure CAP patients without causing unnecessary aspect effects and without contributing to the development of antibiotic resistance, antibiotic therapy should be carefully selected. Although patients with severe CAP should be treated with broad-spectrum antibiotics, patients with non-severe CAP should preferably receive pathogen-directedtherapy. maculation rapid aetiological tests may be useful for targeting initial pathogen-directed therapy, non-rapid tests may support switch from broad- to narrow-spectrum antibiotic therapy and support therapy changes in the case of treatment failure.